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The SCMA IV conference was held in the high-tech Berg Auditorium of the Life Sciences Building at Penn State University in State College PA on June 12-15 2006. Further conference details, registration fees and procedures, lodging, travel and visa information is available via the tabs above. The scientific program is divided into seven topical sessions with Invited Speakers in astronomy or statistics accompanied by Commentators from the other discipline. Brief biographies of the Speakers and Commentators are available here. I Cosmology Istvan Szapudi (Hawaii) Spatial statistics in the cosmic microwave background maps Gary Hinshaw (NASA/GSFC) Statistics in the WMAP experiment Vicent Martinez (Valencia) Cosmic structures: A challenge for astrostatistics Adrian Baddeley (W Australia) Analyzing spatial point pattern data Christopher Kochanek (Ohio State) Understanding quasar microlensing Gary Bernstein (Penn) The statistics of weak gravitational lensing Michael Woodroofe (Michigan) Shape restricted estimation in the search for Dark Matter II Periodic time series John Rice (UC Berkeley) Detecting periodicity in a Poisson process Chris Koen (W Cape) Periodicities in variable astronomical objects Graham Woan (Glasgow) Periodicity in gravitational waves III Recent developments in statistics Christopher Genovese (Carnegie Mellon) Nonparametric Inference in astrophysics and cosmology with application to Dark Energy and the CMB Rebecca Willett (Duke) Statistical analysis of photon-limited astronomical signals and images Merlise Clyde (Duke) Current challenges in Bayesian model choice Alfred Inselberg (Tel Aviv/SDSC) Multidimensional visualization and its applications IV Planetary systems Eric Ford (UC Berkeley) Bayesian model selection and extrasolar planet detection William Romanishin (Oklahoma) Statistics of the colors of Kuiper Belt Objects and Centaurs V Large surveys & mega-datasets Thomas Loredo (Cornell) Recent progress in statistical methodology for astronomical surveys Timothy Axelrod (Arizona) Photometric calibration: An intriguing statistical problem from the LSST Robert Lupton (Princeton) The characterisation, subtraction, and addition of astronomical images Robert Hanisch (STScI/NVO) The Virtual Observatory: Core capabilities and support for statistical analyses in astronomy VI Small-N problems in physics and astronomy Alanna Connors (Eureka) Measuring what we "see" in Poisson images, or, Is that a bridge over the Milky Way? Glen Cowan (Royal Holloway UL) The small-N problem in high energy physics Harrison Prosper (Florida State) Bayesian methods in particle physics: From small-N to large VII Cross-disciplinary perspectives Astronomy: Ofer Lahav (UC London) Physics: Louis Lyons (Oxford) Statistics: James Berger (Duke) Commentators: G. Jogesh Babu (Penn State) Laura Cayon (Purdue) Jayanta K. Ghosh (Purdue) Martin Hendry (Glasgow) Woncheol Jang (Duke) William Jefferys (Texas/Vermont) Ofer Lahav (UC London) Ji Meng Loh (Columbia) John Rice (UC Berkeley) Jeffrey Scargle (NASA-Ames) Jiayang Sun (Case Western Reserve) David van Dyk (UC Irvine) Rebecca Willett (Duke) Michael Woodroofe (Michigan) Zhengyuan Zhu (N Carolina) Scientific Organizing Committee: G. Jogesh Babu (co-chair, Penn State), James Berger (Duke), Eric Feigelson (co-chair, Penn State), Krzysztof Gorski (JPL), Thomas Loredo (Cornell), Vicent Martinez (Valencia), Larry Wasserman (Carnegie Mellon), Michael Woodroofe (Michigan)