Determination of chemical elements in biological fluids and diagnostic substrates from children by inductively coupled plasma mass spectrometryстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:Inductively coupled plasma mass spectrometry was used to analyze diagnostic substrates from newborns and primary school-aged children. We studied urine and blood samples of children aged from several days to 2 months and hair samples of primary school-aged children. Methods for the collection of blood and urine sample were investigated using various medical instruments and different procedures for sample preparation. We studied the effect of sample macrocomponents on the signals from analytes. It was found that sulfur had the largest effect on the intensity of the analytical signal. Methods for assessing matrix effects were considered, that is, the internal standard method and the addition of a matrix component to calibration solutions. The accuracy of the results was confirmed by analyzing certified reference materials and using the standard addition method.