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Efficacy of etoposide chemomobilization in patients with classic Hodgkin lymphomaстатья
- Авторы: Petrova Galina D., Nikiforova Natalia M., Monin Ilia S., Orlova Ekaterina F., Maltseva Larisa Yu, Ogorodnikova Elena V., Grishina Victoria V., Tumyan Gayane S., Tupitsin Nikolai N., Dzhelil Sh Osmanov
- Сборник: Cellular Therapy and Transplantation
- Серия: 13
- Том: 3
- Год издания: 2024
- Место издания: Svetlitsa Saint Petersburg
- Первая страница: 218
- Последняя страница: 219
- Аннотация: Autologous hematopoietic stem cell transplantation (autoHSCT) is the standard of care for primary refractory and relapsed classic Hodgkin lymphoma (r/r cHL). The possibility of auto-HSCT depends on the efficiency of HSC collection, which ranges from 65 to 100%. The success rate of chemomobilization with etoposide at the dose range of 375 mg/m2 to 2400 mg/m2 in patients with cHL, non-Hodgkin’s lymphoma and multiple myeloma varies between 42% and 100%. The present study concerns our experience of peripheral blood stem cell (PBSC) chemomobilization with intermediate doses of etoposide and granulocyte colony-stimulating factor (G-CSF) in patients with r/r cHL. Our objective was to analyze the efficacy and safety of intermediate doses of etoposide in chemomobilization of PBSC in patients with r/r cHL.
- Добавил в систему: Петрова Галина Дмитриевна