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IrCytoToxDB: a dataset of iridium(III) complexes cytotoxicities against various cell linesстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Krasnov Lev, Tatarin Sergei, Smirnov Daniil, Bezzubov Stanislav
- Журнал: SCIENTIFIC DATA
- Том: 11
- Номер: 1
- Год издания: 2024
- Номер статьи: 870
- DOI: 10.1038/s41597-024-03735-w
- Аннотация: Iridium(III) complexes nowadays became rising stars in various health-related applications. Thus, there is a necessity to assess cytotoxicity of the synthesized molecules against cancer/normal cell lines. In this report, we present a dataset of 2694 experimental cytotoxicity values of 803 iridium complexes against 127 different cell lines. We specify the experimental conditions and provide representation of the complexes molecules in machine-readable format. The dataset provides a starting point for exploration of new iridium-based cellular probes and opens new possibilities for predictions of toxicities and data-driven generation of new organometallic anticancer agents.
- Добавил в систему: Калле Паулина