Аннотация:Fractional flow reserve (FFR) is a golden standard for evaluating hemodynamic importance of coronary stenosis. Computed (virtual) FFR has emerged as an effective computational tool for non-invasive FFR evaluation. In this work we present a new web-based computational technology for non-invasive estimation of FFR based on patient-specific data. This technology provides 3D visualization and a graphical user interface. Developed web application virtual FFR does not need to be installed on a local machine (user’s computer) and requires only a browser to get full access to the application capabilities. Calculations are performed with the help of 1D hemodynamic model. Developed approach was tested on a variety of clinical cases. With proper parameters identification, this technology provided relative deviation of the computed FFR from the invasive FFR measurement around 6%.